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Instrument Reproducibility - Example of Variance

Instrument A vs. Instrument B

Even at glance we know Instrument A has superior reproducibility.
(Click the graphic to enlarge.)

MassQC's Control Charts can show if an LC-MS instrument is performing similarly whenever it is run.

The first graph shows an instrument that, except for a few outliers, has consistent, repeatable peak widths over a period of 4 months. In the same time period, the second instrument has a much more variable LC system.

It's noteworthy that outliers are present in both graphs. These may indicated some short-lived problem addressed by the mass spectrometrist during normal operations.

Comparing Operators, Equipment and Procedures

MassQC enables analysis of spray heads, LC systems, sample preparations, and instrument tuning methods. It is a comprehensive feedback tool that leads to better laboratory performance.

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