MassQC Help > Common FAQs          
What does MassQC do?

MassQC analyzes and displays metrics about quality control runs.

What is a metric?

A metric is a numeric value that characterizes some aspect of instrument performance.

What is a quality control run?

A quality control run is an LC-MS/MS analysis of a standard mixture of proteins.

How do I add another quality control run?

Add QC runs by uploading more Thermo LTQ RAW files.

Why am I looking at these particular metrics?

To improve reproducibility in proteomics, the NCI/NIH funded a study called “Clinical Proteomics Assessment Technologies for Cancer (CPTAC)” with:

  • Broad Institute of MIT and Harvard
  • Memorial Sloan-Kettering Cancer Center
  • Purdue University
  • University of California, San Francisco
  • Vanderbilt University School of Medicine

As part of that study, the National Institute of Standards and Technology, NIST, has spent two years refining which metrics are informative.


If you have questions, comments and/or insights about MassQC, you can share them on the MassQC Users Forum.

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