MassQC Help > FAQs > OMSSA          
OMSSA (the Open Mass Spectrometry Search Algorithm) Overview

Before MassQC can compute the values of the metrics for each Quality Control run, the mass spectra for each run need to be searched against a protein sequence database. OMSSA (the Open Mass Spectrometry Search Algorithm) is a database search tool that compares the input spectrum to theoretical spectra generated from a protein sequence database and reads in MGF files generated by ReAdW. OMSSA can be used on any set of protein sequences. in MassQC, OMSSA is used to search these data associated with a simple protein QC sample, such as BSA (Bovine Serum Albumin).

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