MassQC Help > Common FAQs          
What does MassQC do?

MassQC analyzes and displays metrics about quality control runs.

What is a metric?

A metric is a numeric value that characterizes some aspect of instrument performance.

What is a quality control run?

A quality control run is an LC-MS/MS analysis of a standard mixture of proteins.

How do I add another quality control run?

Add QC runs by uploading more Thermo LTQ RAW files.

Why am I looking at these particular metrics?

To improve reproducibility in proteomics, the NCI/NIH funded a study called “Clinical Proteomics Assessment Technologies for Cancer (CPTAC)” with:

  • Broad Institute of MIT and Harvard
  • Memorial Sloan-Kettering Cancer Center
  • Purdue University
  • University of California, San Francisco
  • Vanderbilt University School of Medicine

As part of that study, the National Institute of Standards and Technology, NIST, has spent two years refining which metrics are informative.

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